Gender-specific association of functional <em>prodynorphin</em> 68 bp repeats with cannabis exposure in an African American cohort
نویسندگان
چکیده
منابع مشابه
An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity.
A highly heritable and reproducible measure of asthma severity is baseline pulmonary function. Pulmonary function is largely determined by airway smooth muscle (ASM) tone and contractility. The large conductance, voltage and calcium-activated potassium (BK) channel negatively regulates smooth muscle tone and contraction in ASM. The modulatory subunit of BK channels, the beta1-subunit, is critic...
متن کاملAssociation of substance use disorders with childhood trauma but not African genetic heritage in an African American cohort.
OBJECTIVE Genetic variation influences differential vulnerability to addiction within populations. However, it remains unclear whether differences in frequencies of vulnerability alleles contribute to disparities between populations and to what extent ancestry correlates with differential exposure to environmental risk factors, including poverty and trauma. METHOD The authors used 186 ancestr...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولGender Differences in Preclinical Markers of Kidney Injury in a Rural North Carolina African-American Cohort
INTRODUCTION The incidence rate of end-stage renal disease (ESRD) is highest among African-American (AA) males. The reason for this disparity in ESRD for AA males remains unclear, but it is well established that diabetes is the leading risk factor. Prediabetes may also be a risk for kidney disease since prediabetics have increased risk for cardiovascular disease and often do not receive drug in...
متن کاملCannabis use patterns and their association with DSM-IV cannabis dependence and gender.
AIMS To investigate the gender differences in the patterns of cannabis use (CU), namely frequency, times of day, social context and methods and in their association with DSM-IV cannabis dependence. METHODS A sample of 3,904 students from German universities was recruited via an internet survey. Logistic regressions and associated areas under the ROC curve (AUC) were calculated among current c...
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ژورنال
عنوان ژورنال: Neuropsychiatric Disease and Treatment
سال: 2018
ISSN: 1178-2021
DOI: 10.2147/ndt.s159954